Unlike steroids, the drug has minimal impact on the immune system. The Janus kinases (Jaks). View more. A blinded, randomized, placebo-controlled trial of the efficacy and safety of the Janus kinase inhibitor oclacitinib (Apoquel) in client-owned dogs with atopic dermatitis. Bursatti, Leeches) in Dogs, Cats and Horses. For maintenance therapy, the same dose (0.4 to 0.6 mg oclacitinib/kg bodyweight) should then be administered only once a day. 27. We cannot be sure of accurate dosing when tablets are quartered, and thus this practice is not recommended. 2: The Barn and Pasture: Horses with Summer-Pasture-Associated disease usually have less symptoms when kept in the barn during the warmer months. You can give your dog Apoquel with or without food. Rest assured, your horses are receiving the best possible disease protection. I have not tried to go less than that. Weve been doing really well with every other day dosing. I had a cat on it years ago and it was $$$$ but it was the only thing that worked for her. Adding an update here in case its helpful for others. Ordering patient medications is easy. Lopes NL, Campos DR, Machado MA, et al. This makes it a common site for the bodys expression of allergic reactions. Long term itch reduction. Powered by Discourse, best viewed with JavaScript enabled. Specifically, studies in cats have used the following dosage: Initially, doses ranging from 0.4 to 1.2 mg/kg body weight, twice daily, for 24-28 days. 9. Rarely, dogs on Apoquel develop new skin masses; however, a long-term study found no association between Apoquel and the development of malignant cancer. And some can got a lower dose or a further spread out dose. Excitement rather than lethargy can occur occasionally, especially in cats. In fact, in our recent study evaluating almost 400 potential allergens, latex proteins were the most significant allergens for diagnosing severe equine asthma.. How Should It Be Given? Meaning, if a 100lbs dog gets 16mg (1 pill), a horse does not need 160mg (10 pills). Generally self-limiting and harmless, hives are nonetheless uncomfortable and can occasionally lead to angioedema (swelling under the skin) or purpura (blood vessels rupturing and leaking blood internally). In severely affected horses, we would expect to see lower airway inflammation and airway obstruction, manifesting as increased respiratory effort, frequent coughing, mucous buildup, and exercise intolerance, White says. Vet Dermatol 2017;28(5):512-e123. Allergen avoidance and allergen-specific immunotherapy are measures that address the allergy itself; various drugs are available for symptomatic management. Eur J Pharmacol 2017;794:20-26. So I think cost becomes dependent on that. If the horse is allergic to any of them, his immune system elicits a response, and a hive forms at the injection site. However, the twice-daily use must not last for more than 14 days. Option 3 is using a nebulizer with dexamethasone and/or other drugs. Intradermal allergy testing is the gold standard for this and involves a veterinary dermatologist subcutaneously injecting very small quantities of potential allergens into a clipped patch of the horses neck. FALL 2019. m. Editor: Norma White-Weithers, MS, DVM, DACVD Veterinary Allergy & Dematology Consultant, Baldwin, NY 11510 Work: 646-329-4719 . Dexamethasone is a synthetic corticosteroid hormone used to manage inflammation in diseases or conditions in which the immune system has a significant role. I did not know about this, but considering Im going through apoquel at a reasonable rate this sounds like it would be worth signing up for. Allergies primarily affect the immune, respiratory, and integumentary (skin) systems and, if unmanaged, can seriously impact an animals performance and well-being. Schindler C, Levy DE, Decker T. JAK-STAT signaling: from interferons to cytokines. Vet Dermatol 2019;30(2):87-90. The Feed: One of the most common recommendations for managing Equine Asthma has always been to stop feeding hay. Initially, the recommended dose of 0.4 to 0.6 mg/kg should be given twice daily for up to 14 days. Recently, we have found that latex, which is everywhere in the horses environmentembedded in riding surfaces and racetracks, for examplemay be associated with severe equine asthma, he says. Give one chewable per month to the dog. By blocking cytokines, Apoquel blocks your dog's skin from itching and inflammation. Frank RK, Galvan BA, Schoell AR, et al. Despite its delayed effects, cyclosporine is still a popular drug to treat canine atopic dermatitis because in some cases it can be dosed every other day or even every third day after initial daily treatment. Vet Dermatol 2015;26(4):235-e52. If you struggle to get your dog to take tablets, you can try hiding it in their food, or wrapping it in a tasty piece of meat. on various factors. Search term . Both can be very serious. Since oclacitinib is a rather weak anti-inflammatory drug, it was suggested that remission of active moderate to severe atopic dermatitis be induced with a course of a broad inflammation-targeting drug, such as a short-acting glucocorticoid, until clinical signs become mild. Rectal Prolapse in Dogs and Cats. Quartering tablets is extra-label use. A follow-up study assessed the long-term safety, efficacy, and quality of life of oclacitinib-treated dogs. This gives you the total number of milligrams for the dose for your horse. 3. Dosage and treatment schedule The recommended initial dose is 0.4 to 0.6 mg oclacitinib/kg bodyweight, administered orally, twice daily for up to 14 days. Serious side effects include seizures, abnormal breathing, incoordination, muscle tremors, and coma. Noli C, Matricoti I, Schievano C. A double-blinded, randomized, methylprednisolone-controlled study on the efficacy of oclacitinib in the management of pruritus in cats with nonflea nonfood-induced hypersensitivity dermatitis. The second option is serum (blood) testing. These and other kinase-inhibiting drugs sometimes work very well to stop the itching. For the first two weeks, this is to be given twice per day, and then once per day after the first two weeks for maintenance. Pasture-associated equine asthma is most prevalent during the summer in the southeastern U.S. but has been reported worldwide. Minimum order 6 tablets per dosage. Gonzales AJ, Bowman JW, Fici GJ, et al. It is initially prescribed twice daily for 14 days, then once daily for maintenance therapy. In the past 5 years, however, oclacitinib (Apoquel; zoetisus.com), a Janus kinase (JAK) inhibitor, has become another important drug in the management of allergic pruritus. But I had my mare tested last year, she also came up allergic to some foods (flax being one) for which I was told serum was not an option. Loft K, Simon B. No texts please., Horse breeding from planning through foal care, Horse-health-problem risk factors, prevention, diagnosis, and treatment, Design and maintain a healthy horse operation, Prevention and treatment for problems of the equine foot, How to care for the basic health needs of horses, Prevention, diagnosis, and treatment of leg lameness, Proper feeding practices for foals, adult horses, and older horses, All aspects of caring for performance horses, News and issues for equine health professionals, Discussions about the welfare of our equine friends. Cosgrove SB, Cleaver DM, King VL, et al. Designed by Elegant Themes | Powered by WordPress, You need to be logged in to fill out this form. Really? 1,2 For over 30 years, Adequan i.m. While easy to perform, Fultz says its not always accurate at predicting the exact allergens. Apoquel can only be obtained with a prescription; it is available as film-coated tablets and chewable tablets in different strengths to cover a range of dog weights. The bodys largest organ, the skin serves as the immune systems first protective barrier. Not really cheap any way you shake it, but considering that she was on zyretc, dex, smarthbreathe ultra, respi-free previously. I hear the result have been spectacular. Oclacitinib should not be given in dogs younger than 12 months of age due to an increased risk for activating demodicosis, bacterial pneumonia, and other serious infections. 2022 Zoetis Services LLC. Repeated oral dose tolerance in dogs treated concomitantly with ciclosporin and oclacitinib for three weeks. Until recently, glucocorticoids (systemic and/or topical) and cyclosporine have been considered the most effective symptomatic treatment options to manage atopic dermatitis.5 Oclacitinib is now also an effective option (BOX 1). Saridomichelakis MN, Olivry T. An update on the treatment of canine atopic dermatitis. The most common practical starting dosage for many cats is of the 5.4mg tablet, or 2.7mg. The drug targets pro-inflammatory proteins, called cytokines, responsible for itching and inflammation, relieving signs of skin allergies. These reports suggest the potential use of oclacitinib in, While oclacitinib is a very effective and fast-acting. Im glad that youve found a solution- but, after the allergy testing you can start them on a regimen designed exactly for what they are allergic to, which will help to desensitize them to those allergens. I had my dog on it and the price was pretty steep. Oclacitinib was well tolerated in both studies. Trials showed that spreading out dosing was more successful than lowering. The frequency of urinary tract infection and subclinical bacteriuria in dogs with allergic dermatitis treated with oclacitinib: a prospective study. Some allergic reactions are unexpected, as White has realized through his research. This study showed that pruritus was improved in only 42% of the study population; thus, use of oclacitinib in cats did not seem to be as effective as in dogs.17 A follow-up study was conducted with a higher dose (0.7 to 1.2 mg/kg) and a longer induction period (28 days). Cosgrove SB, Wren JA, Cleaver DM, et al. Is it possible to cure an allergy? Dawn M. Cleaver, DVM Associate Director, Regulatory Affairs Skin allergies can also cause pruritus (itching) and associated hair loss. Download Apoquel Information Sheet. One of my horses was tested at New Bolton (he has since passed away) and I was told that a serum wasnt possible or effective for most of his food-bourne allergies. Even though the drug is currently labeled for use in dogs (with allergic dermatitis), initial studies show that horses absorb it well, Fultz says. The powerful network of cells and antibodies known as the immune system can recognize dangerous invaders and disarm them before they hurt the host. Having allergy tested 3 horses you can get a serum for some allergens but not all. Dexamethasone commonly is used in horses to treat allergic reactions such as respiratory allergies, chronic obstructive pulmonary disease (heaves), hives, itching and inflammatory diseases including arthritis. After that it would be about $250 every 6 weeks or so if I cant further reduce time between pills. 12. Many allergic reactions are evident as a mild case of transient hives. Apoquel Overdose Information Dogs that received overdoses in safety studies had side effects that included one or more of the following: vomiting, diarrhea, cysts between the toes, skin inflammation, papilloma's (warts), pneumonia, enlarged lymph nodes, and decreased blood cell production. 1. He stayed on as a faculty member until 2013, when he decided to move back to Switzerland to open his own dermatology clinic in his hometown of Basel in 2014. Innovation is constantly occurring in the field of immunotherapy. In atopic dermatitis, it is mainly mediated by a large group of proinflammatory and proallergic Th2 cytokines (e.g., interleukin [IL]-4, IL-5, IL-10, IL-13, IL-31). Transdermal applicator that gives easy & accurate dosing every time. 14. Apoquel should be administered orally, twice daily for up to 14 days, and then once daily for maintenance therapy. 2. More studies are necessary to confirm oclacitinibs effects in non-allergic diseases and what other immune-mediated mechanisms may be involved. Vet Dermatol 2015;26:134 (abstract). Pulsoni D, Freire A, Ferreira DR. Juvenile-onset ischemic dermatopathy in two dogs treated with oclacitinib. In the past 5 years, however, oclacitinib (Apoquel; ), a Janus kinase (JAK) inhibitor, has become another important drug in the management of allergic pruritus. Apoquel Dosage in Dogs Apoquel tablets for dogs comes strengths of 3.6mg, 5.4 mg and 16mg of oclacitinib per tablet. APOQUEL FOR DOGS DOSE. Treatment will probably need to repeated somewhere between 1 and 6 weeks after the initial treatment course. It is important to address that the use of oclacitinib in cats is off-label, and owners should be informed before using oclacitinib in this species. 4. APOQUEL may be administered with or without food. Since oclacitinib has been shown to be comparable to prednisolone, oclacitinib can be a good alternative to prednisolone when combined with cyclosporine for initial treatment. APQ-01043R3, halved to ensure that the ingredients are equally distributed. Stay on top of the most recent Horse Health news with, If interested in adopting this horse, please submit an Adoption Inquiry via our website: Allaboutequine dot org. Merck & Co., Inc., Rahway, NJ, USA (known as MSD outside of the US and Canada) is dedicated to using the power of leading-edge science to save and improve lives around the world. That something could very well be allergy-induced asthma. So new drugs such Atopica and Apoquel are prescribed routinely, to help dog owners find a quick fix for dog allergies. A Magnawave-certified practitioner, Lucile also runs a small equine PEMF therapy business. Treatment should be started at a dose of 0.4 - 0.6 mg per kilogram bodyweight twice a day for up to two weeks. Cats have been reported to drink more water while receiving this drug and also experience be- havior changes while receiving hydroxyzine. Table of Contents hide Apoquel dosage for dogs chart Apoquel for Dogs Reviews: Does It Really Work? Fukuyama T, Ganchingco JR, Bumer W. Demonstration of rebound phenomenon following abrupt withdrawal of the JAK1 inhibitor oclacitinib. APOQUEL tablets may be administered with or without food. The steroids are usually given orally, but we may want to start with injections for a week or so in severely affected horses. Ordering your pet's prescription drugs from Wedgewood Pharmacy is safe, and convenient. 7. I spend $150 a month on my horse on apoquel. Dexamethasone: EZ Dose Micro Transdermal Gel, Dexamethasone: Twist-a-Dose Transdermal Gel, Discussion Guide for Pet Owners and Veterinarians, Medication Information for Pet and Horse Owners. Cyclosporine, which is approved for the treatment of canine atopic dermatitis, has an onset of efficacy of up to 4 weeks. The mare luckily didnt have a lot of food allergies and eliminating flax wasnt a big deal. not random, very relevant and helpful! She gets it all year long since she has a full list of allergies including dust, feathers, and cat dander along with grasses. This content is intended for counseling purposes only. It can be given with or without food. Interestingly, the results suggest that oclacitinib has immunosuppressive properties, but only at a higher dosage than that approved on the label. A follow-up study assessed the long-term safety, efficacy, and quality of life of oclacitinib-treated dogs. Oclacitinib is well tolerated and, compared with classic allergy medications such as glucocorticoids and cyclosporine, equally effective in controlling pruritus. Allergen avoidance and allergen-specific immunotherapy are measures that address the allergy itself; various drugs are available for symptomatic management. Vet Dermatol 2019;30(2):110-e30. A blinded, randomized clinical trial comparing the efficacy and safety of oclacitinib and ciclosporin for the control of atopic dermatitis in client-owned dogs. ACVIM, a Florida-based large animal internal medicine specialist with an interest in respiratory disease. When working with a liquid: Multiply your horse's weight in pounds times the dose rate in milligrams per pound. More severe ones, however, can truly take a toll on your horses health and make him miserable. Proc (Bayl Univ Med Cent) 2018;31(4):524-525. 14. Works on all common sources of allergens. These are known as allergy shots. I am not saying it is a cure all, but that and some generic Zyrtec make my mare a whole lot more comfortable. The pharmacokinetics of oclacitinib maleate, a Janus kinase inhibitor, in the dog. So I want to make sure she has the support she needs to acclimate to hot humid summer weather. Pros and cons of oclacitinib therapy. Vet Dermatol 2016;27(1):22-e7. Unlike steroids, the drug has minimal impact on the immune system. Topics. Renal Anemia, or . While this is a very important strategy for some types of Equine Asthma ("classic" RAO), it may not be as important when managing those with Summer-Pasture-Associated disease. Noli C, Matricoti I, Schievano C. A double-blinded, randomized, methylprednisolone-controlled study on the efficacy of oclacitinib in the management of pruritus in cats with nonflea nonfood-induced hypersensitivity dermatitis. To overcome its delayed effect, cyclosporine is often initially combined with other drugs such as prednisolone to accelerate the anti-inflammatory and antipruritic effects. Lopes NL, Campos DR, Machado MA, et al. This site is for US animal healthcare professionals. Maintaining Your Horses Weight During the Winter, Special Report: Preventing 3 Common Equine Joint Issues, JACKSON- Gelding/Bay/Mustang (Nevada) - Project/Ready for Training, JENNINGS Gelding/Cremello/Mustang (BLM) Ridable (Green), recent study evaluating almost 400 potential allergens, BONNIE: Sorrel Mustang Mare Non-Riding Companion Only. Oral . Im hoping those are things I can stop giving, so that will help some with overall cost. 2019;30(3):201-e63. For years, glucocorticoids and cyclosporine have been used for the symptomatic management of atopic dermatitis, including the associated pruritus. Her allergies have reared their ugly heads again - no jowl pyoderma, but ears itching. Clenbuterol dilates the airways, and may improve air flow, but it doesn't treat the inflammation associated with the disease. Apoquel is the #1 prescribed medicine for fast, effective relief of allergic itch and inflammation due to atopic and allergic dermatitis 1 Indications Control of pruritus associated with allergic dermatitis and control of atopic dermatitis in dogs at least 12 months of age. A newer prescription drug, Apoquel (oclacitinib) has recently hit the market and might prove useful for allergic horses. Efficacy and safety of oclacitinib for the control of pruritus and associated skin lesions in dogs with canine allergic dermatitis. A newer prescription drug, Apoquel (oclacitinib) has recently hit the market and might prove useful for allergic horses. Ortalda C, Noli C, Colombo S, et al. In this study, 70% of the study population receiving oclacitinib showed improvement in pruritus compared with 75% in a group receiving methylprednisolone.18 Based on this study, a higher dose with a longer induction period seems to be the key to successfully treating feline pruritus with oclacitinib. Assuming you cannot contact your vet: For hives or possible allergic airway disease (heaves), for a 1000 lb horse, give 5-10 tabs of 25mg diphenydramine crushed up and mixed in water and dosed in a syringe orally (by mouth). 1,2 The #1 prescribed medicine for allergic itch in dogs. Vet Dermatol She adds, however, that some horses allergy signs are so dramatic that corticosteroids are the most logical choice, at least initially. She reports choosing Apoquel over corticosteroids in several of her allergic patients that are also at risk for developing laminitis. Unlike some other allergy. Apoquel Dosage for Dogs. Apoquel doses are usually between .04-.06 milligrams per kilogram of body weight (mg/kg) . Before your vet administers immunotherapy, though, you must identify your horses respiratory and skin allergies. This product is top-dressed onto the feed and helps horses with equine asthma, including heaves in older horses and inflammatory airway disease in young, athletic horses.". Yes, we looked into this approach, but unfortunately it was not a viable option for my horse for a variety of reasons including other health factors and severity of allergies. Apoquel has not been tested in dogs receiving some medications including some commonly used to treat skin conditions such as corticosteroids and cyclosporines. She has a master's degree in animal science from the University of Delaware and graduated from the University of Pennsylvania School of Veterinary Medicine in 1982. 15. Zyrtec: The human antihistamine may be beneficial in a small proportion of horses with Equine Asthma. Apoquel delivers onset of relief within 4 hours and effectively controls itching within 24 hours. Since oclacitinib has been shown to be comparable to prednisolone, oclacitinib can be a good alternative to prednisolone when combined with cyclosporine for initial treatment. Why Do Some Horses Develop Respiratory EHV-1 and Others EHM? She is a New-York-based freelance author with a passion for equine health and veterinary care. The compounded medications featured in this content have been prescribed and/or administered by prescribers who work with Wedgewood Pharmacy. This encourages the natural drainage of irritants, allergens, and bacteria from the airways.. Most recently, it was suggested that the treatment strategy for canine atopic dermatitis might need to be adjusted. Several reports of successful use of oclacitinib to treat other diseases have been published.22-29 They include several cases of immune-mediated vascular diseases: idiopathic ear tip vasculitis in 4 dogs26 and ischemic dermatopathy in 6 dogs.28,29 In these reports, other classic medications had failed to control the disease until oclacitinib was added. While oclacitinib is a very effective and fast-acting antipruritic drug, the decision of when to use it depends on various factors. Apoquel is a prescription dog allergy medicine used for the control of itch associated with allergic dermatitis and control of atopic dermatitis in dogs 12 months and older. Owners using a nebulizer will also have to replace the medication cups on the nebulizer every few months, at a cost of about $80 per cup. Treatment may then be continued at the same dose given once a day. If she suspects a product or ingredient to be the source of an allergic reaction, Fultz recommends performing elimination trials. Pre-slaughter withdrawal time is 14 days following the last dose. 25. There are two types of this condition, summer-pasture-associated and classic recurrent airway obstruction (RAO). Vet Dermatol 2014;25(6):512-518. This content is informational/educational and is not intended to treat or diagnose any disease or patient. 23. While efficacy was comparable to that observed in the previous studies, significant positive effects on the dogs quality of life were observed in >91.5% of cases after 630 days. and unfortunately grass and dust are the main culprits. Do not use in breeding, pregnant, or lactating dogs. During this period, the drug is administered twice daily, with an interval of 12 hours. Gonzales AJ, Humphrey WR, Messamore JE, et al. Equine Regenerative Therapies for Managing Arthritis in Horses, Infographic | 12 Smart At-Home Biosecurity Practices for Horse Owners, Infographic | How To Keep Your Horses Joints Healthy. The tablets come in three dose sizes: 3.6mg 5.4mg 16mg Always give the dose prescribed by your veterinarian. Hay replacement consists of any of the following: a complete pelleted diet, soaked alfalfa cubes, hay pellets, or possibly a bagged forage product like Chaffhaye. 25. 3. This drug has been used in dogs with some pretty fabulous results. Fultz adds that over time this process teaches the immune system to tolerate exposure to substances it previously considered irritating. Olivry T, Banovic F. Treatment of canine atopic dermatitis: time to revise our strategy? For years, glucocorticoids and cyclosporine have been used for the symptomatic management of atopic dermatitis, including the associated pruritus. Successful treatment of atopic dermatitis with the JAK1 inhibitor oclacitinib. If the patient remains stable and other controlling measures-such as allergen avoidance, allergen immunotherapy, and preventive topical therapyhave been implemented, the use of oclacitinib can be limited to flare control. They result in the production of antibodies that block the allergy-causing IgE from recognizing the allergen, thus preventing the associated symptoms.. 28. Apoquel Oclacitinib Used for Pet Meds MORE expand_more savings GoodRx lowest price $75.90 (Save -22%) local_offer Avg retail price $62.49 medication Availability Brand only Get 20% off your first order with code GOODRX20 Shop Apoquel at America's #1 Pet Pharmacy for the best pet prescription medications online! This treatment option is FDA approved for equine asthma, and is very safe with no known side effects. Use of oclacitinib (Apoquel; Zoetis) for treatment of cutaneous mastocytosis in a cat. 30. How Organized Are Your Horses Health Records? Use of oclacitinib (Apoquel; Zoetis) for treatment of cutaneous mastocytosis in a cat. Licorice Roo t (Glycyrrhiza glabra) This sweet and soothing herb has been used medicinally for over 3,000 years. 6. The recommended dose of Apoquel for dogs is 0.18 to 0.27 mg per pound of body weight. Oclacitinib (APOQUEL) is a novel Janus kinase inhibitor with activity against cytokines involved in allergy. To overcome its delayed effect, cyclosporine is often initially combined with other drugs such as prednisolone to accelerate the anti-inflammatory and antipruritic effects. Gonzales AJ, Bowman JW, Fici GJ, et al. A blinded, randomized clinical trial comparing the efficacy and safety of oclacitinib and ciclosporin for the control of atopic dermatitis in client-owned dogs. 2. has been administered by veterinarians to help horses of . Side effects have been rarely seen and documented, but the most common occurrences have been mild vomiting and diarrhea. These animals require the opposite regimen. The dose range is very strict, I do not recommend going above the recommended dose due to immune suppression, below the range and it doesn't seem to work in most cases. 28. 19. Such an immune response is essential for survival; it protects against all sorts of pathogens, from bacteria and viruses to fungi and parasites. You are encouraged to speak with your prescriber as to the appropriate use of any medication. Barns can also have noxious gases from the ammonia in urine. She added, "Studies show that omega-3 fatty acids help horses with equine asthma. For dogs weighing between 10 and 14.9 pounds, give of a 5.4 mg tablet twice daily as dosage. On the topic of simple and economical allergy management, a readily accessible ingredient that helps many horses is, Recently, we have found that latex, which is everywhere in the horses environmentembedded in riding surfaces and racetracks, for examplemay be associated with severe equine asthma, he says. She has been allergy tested! Its an annoying pill schedule to keep track of, but my boarding barn has been great about it. Vercelli A, Cornegliani L. Use of oclacitinib in treatment of canine idiopathic ear tip vasculitis. Pollen and other plant-based aeroallergens are the source of their distress, and they fare much better inside a well-ventilated barn. Allergies are generally managed based on the severity of clinical signs. Uses for Apoquel Feline idiopathic ulcerative dermatosis treated successfully with oclacitinib. Adverse events were reported in less than 5% of dogs, including urinary tract infection, vomiting, otitis, pyoderma, and diarrhea. Discount Prices on Pet Supplies, Nexgard, Bravecto, Trifexis, Simparica TRIO, Apoquel, and more. @vxf111 we were told the same thing for food allergiesthat they did not make serums fot them because they were not very effecttive and the the expectation was that the allergen be removed from the diet. Cochet Faivre N, Degorce-Rubiales F. Clinical eosinophilic popular dermatitis associated with histological eosinophilic granuloma rapidly responsive to oclacitinib in an adult Labrador retriever. She reports choosing Apoquel over corticosteroids in several of her allergic patients that are also at risk for developing laminitis. Allergies primarily affect the immune, respiratory, and integumentary (skin) systems and, if unmanaged, can seriously impact an animals performance and well-being. Immunomodulatory in vitro effects of oclacitinib on canine T-cell proliferation and cytokine production. Qualifies for Zoetis Petcare Rewards! Recently, researchers have delved into the causes and consequences of what now falls under the umbrella term equine asthma. Allergies can develop at any time, in any horse, and seemingly for any reason. Initially, the recommended dose of 0.4 to 0.6 mg/kg should be given twice daily for up to 14 days. Your Price: $2.20. If you mix it in their food, ensure that your pet chews the treatment rather than swallowing it without chewing for effective results. APOQUEL may be administered with or without food. Panteri A, Strehlau G, Helbig R, et al. Its an easy and cost-free strategy you can do yourself. The frequency of urinary tract infection and subclinical bacteriuria in dogs with allergic dermatitis treated with oclacitinib: a prospective study. For more information, please see the full Prescribing Information. Yamaoka K, Saharinen P, Pesu M, et al.
Comments are closed.